Dr. Amy Larsen must navigate an unfamiliar world after a brain injury erases the last eight years of her life. She can rely only on her estranged 17-year-old daughter, whom she remembers as a 9-year-old, and a handful of devoted friends, as she struggles to continue practicing medicine, despite having lost nearly a decade of knowledge and experience.
Revelations about Amy's brain health put her future at Westside in jeopardy. Gina pushes the limits of medicine to revive a patient who seems beyond saving. Meanwhile, Ben begins human trials on his artificial heart implant.
Amy and Jake work together to treat a patient whose secret past puts her life in danger; after a key donor withdraws funding, Ben must scramble to save his artificial heart trial; Sonya and TJ's relationship is tested when Sonya's father visits.
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